Cervical Cancer Research

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Cervical cancer is amongst the most hazardous cancers as it causes around 290000 deaths every year all around the world. Women vulnerable to this cancer are around or below 35 years of age. Nevertheless, there is a rigorous and effective research work going on for this disease.

Cervical cancer research is aimed at various things such as discovering the exact cause for the disease, possible preventive measures to avoid the disease and various breakthrough of cervical cancer medications and vaccinations to develop immunity to this disease.

No overnight change can be expected to combat the mortality rate of the disease, but with every passing year the research seems to come closer to make this disease curable to some more degree than the past year.

The importance of screening in early detection of cervical cancer and thereby saving the lives of most of the women suffering this condition by curing it completely is understood in the recent decades. This has proved to be a vital factor as the cervical cancer death rates have tremendously dropped down. Once second largest death-causing cancer in U.S. has now dropped to the 14th position to cause mortality.

Research Areas of Cervical Cancer: Research studies for cervical cancer are aimed at developing new screening techniques, and treatment techniques that offer better promising results. There are some vaccinations undergoing research studies to seek a preventive measure from cervical cancer. Following are some of the main research studies going on around the world:

  • HPV Vaccines - Vaccines provide prevention from certain diseases. There are certain types of HPV strains that are closely linked with cervical cancer. Two common types of HPV virus types are HPV 16 and HPV 18.

    Research trials have shown positive results for vaccination developed to combat these strains of HPV. Vaccinations currently developed and available are specifically intended to provide immune effect to these two types of HPV types. Hence, incidences of cervical cancer will be reduced over time because women, exposed to these two harmful strains of the virus will not develop HPV infection (that usually leads to cancer), if they have received the vaccination.

    The research work is still continued to develop vaccine for preventing infections from other types of HPV strains as well. Apart from the preventive vaccines, curing vaccinations are also under research studies that seek a treatment for HPV infection. Women, who fall prey to HPV infection, are given experimental vaccinations to strengthen the immune system so as to kill the virus and heal the virus before it develops any cancerous lesions.

    Research trials are also seeking a solution for metastasized cancer, in which cases a few virus are considered to boost the growth of the cancerous cells. The vaccinations for advanced cancer are supposed to strengthen immune response to such cancer-causing virus and arrest the cancer cell growth.

  • Screening Tests - Research is being conducted to look for better screening tests that can catch even small and earliest cancer lesion or HPV infection. HPV, messenger RNA is a test amongst the new research trials that is capable of yielding exact and precise result than the currently available tests for the disease.

    More sensitive and collaborative approach is being made by scientists over the world to develop specific tests which can diagnose and detect tiny cervical abnormalities. Also, efforts are put in to help cervical cancer be more preventive.

    To make this disease preventable, availability of affordable screening tests is vital. Hence, efforts are put in to introduce a more affordable HPV testing. Also, studies are directed to develop home-test for HPV infections, which can produce accurate results in the same day.

  • Disease Treatment - For the betterment of the treatment, researchers are developing new treatment approaches. Research trials are intended to look for new anti-cancer drugs and also a new combination of drugs.

    Different new methods to administer these drugs either orally or through chemotherapy and variations of dosages and schedules are tried. New combinations of the therapeutic treatments and surgery are also under research to offer better life expectancy.

    Researchers have also learned in depth of certain mutations in the cells and genes that may lead to cancer over time. Hence, a targeted therapy is being tried that involves a drug therapy intended to combat and arrest these gene mutations. Such drugs act effectively over the cancer cells while producing fewer adverse effects. Pazopanib is one of the drugs used for this therapy.

  • Radiation Therapy - Radiation therapy comes under standard treatments of cervical cancer. However, enhancement and betterment of this therapy is also on the agenda of the research trials. Certain radiation sensitizers are studied that can make radiation therapy more effective and help kill more cancer cells effectively.

    Also as per few researchers, hyperthermia condition (raised temperature of the body) is also helpful to improve the efficacy of radiation therapy and stopping it from recurring.

  • Pre Cancerous Treatment - Currently pre cancerous lesions are treated with laser treatment or cryotherapy. However, researchers are seeking drug trials to treat initial cancer lesions in some patients.

Diindolylmethane and cidofovir are two drugs tried successfully in some patients and have shown good results. However, studies are still continued to make it as a standard treatment.

Cervical cancer research is going on to offer better cure for the disease. The clinical trials are intended to serve various purposes such as seek a new combination of radiation therapy and chemotherapy, new schedules for radiation therapies, new drug combinations for chemotherapy, introducing new treatment therapies and so on.

The research work is going on all over the world to offer optimum life expectancy to the patients with better quality of life. There are some vaccines being studied that can be administered in boys so as to avoid the occurrence of the disease in men. Better vaccinations and treatment techniques are under trial to offer a promising future for the cervical cancer patients.

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