Endometrial Cancer Breakthrough and Research

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Endometrial cancer breakthrough deals with some innovative approach to treat this disease. A number of techniques are evolved to diagnose the development of cancer cells in the body. Curing the uterine cancer has become possible these days, due to the advancement in the researches and studies.

One study carried out by the scientists revealed that inducing certain inhibitor medicine r in a patient with endometrial cancer is helpful to restrain the receptors in the cell that stimulate the growth of tumor in a particular group of patients with uterine cancer. This inhibitor drug worked well even on the uterine cancer cells that contain a usually occurring PTEN, mutant gene or other previously used drug treatment. This was a successful endometrial cancer breakthrough.

Alteration of FGFR2 gene:

A team of researchers have discovered the unnoticeable mutations in the development of a fibroblast factor receptor. This receptor is termed as (2 FGFR2) gene. Out of 100 a bout 15 women with endometrial cancer have an altered form of FGFR2. This form of tumor signifies 80 percent of all uterine cancers. Recent treatment for uterine cancer can comprise of surgical removal, chemotherapy and radiation therapy. Although, these treatments works effectively on majority of women to eliminate the cancer cells or decrease their growth, around 15 percent among those undergoes a persistent recurrence that are defiant to the existing drug therapies.

The endometrial cancer research which revealed that FGFR2 inhibitor can be used to eliminate the cancer cells c (even when they are associated with other genetic complications) during this cancer, proves that the anti-FGFR2 therapies have high potential to kill the cancer cells.

Endometrial cancer facts: Uterine cancer which develops in the inner lining of the womb (uterus). It is one of the most popular gynecological cancers in the U.S. This year above 40, 000 patients are diagnosed with this cancer among which 7500 are at higher risk of mortality. This estimate is given by the American Cancer Society. As per the surveys, only lung, colon and breast cancer strikes with greater frequency. Since, endometrial cancer develops very slowly and usually can not be diagnosed until after the age of 60 years, about one woman in the group of eight who are examined with this cancer may have possibilities to die before five years.

Targeted drug therapy:

Targeted drug therapy can be referred as an innovative attempt of uterine cancer treatment. It depends on the identifying the the anomalies in cancerous cells that stimulates them to develop hysterically. In this treatment the cancer cells are treated with certain drugs that can help to restrain the genetic abnormalities.This therapy increases the scope of the oncologists to counterpart the treatment to the particular genetic identification of each patient. This strategy works well in other cancer types (lung cancer, breast cancer and leukemia) as well. Innovative Endometrial Cancer Research:

Tumor markers:

Recurrence of some type of cancer can be detected by the release of certain molecules. For example, CA 125 works as a marker in detecting the ovarian cancer recurrence. Recent studies found that CA 125 blood tests can be useful to detect the endometrial cancer recurrence. This can be detected more early before it can be seen in the MRI and CT scans.

How mutation in molecules develops cancerous cells?

Recent endometrial cancer research has shown how mutation in certain molecules can convert a normal cell in to a cancerous cell. It is a known fact that the damaged and old cells in the endometrium are responsible for the growth of cancer cells. If these genes get damaged and become uncontrollable they get converted in to cancer. Hereditary is one of the other reason which gives rise to this cancer cells in a person.

Surgery and other Treatments:

If your cancer is not detected in the early stages, it may get spread in to the nearby lymph nodes and move ahead towards other distant organs. As per the endometrial cancer breakthrough, surgery is an ideal option to remove the cancer cells completely from the uterus. After surgical removal, radiation therapy is used to avoid the recurrence of cancer cells in the endometrium or nearby area. If the cancer gets spread into the adjoining lymph nodes, even the lymph nodes can be removed.

In sentinel lymph node biopsy, a blue dye or a radioactive tracer is induced into the area suspicious to cancer. The lymph nodes with dye will turn blue while the lymph nodes with tracer become radioactive. These lymph nodes are examined closely and are removed through surgery.

New additions in the endometrial cancer breakthrough can be seen, since a number of researches are carried out often. Researchers deals with new discoveries to prevent the cause of cancer or reduce the development of cancer cells in the body.

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