Tongue Cancer Research
In order to treat tongue cancer effectively, number of new clinical trials and researches have been evolved. In some institutes, the specialists of radiation oncology, neck and head surgery, molecular medicine, immunology and hematology collaborates to perform a research seeking to incessantly develop the treatment options of the cancer patients. A range of innovative techniques are used by the researchers and scientists to ensure advancement in tongue cancer research.
How Transoral Robotic Surgery Can Help to Treat Tongue Cancer?
Some researchers, who deal with the researches related to the head and neck, studied the application of transoral robotic surgery to treat tongue based cancer. Outcomes of the study confirmed that transoral robotic surgery is effective and safe, and may result into few side effects or complications. As compared to the traditional techniques, this treatment shortens the post-surgery recovery term of the patient. By considering the fact that transoral robotic surgery has more positive outcomes, most of the surgeons have adopted this treatment option on a large scale.
How HPV Vaccine Can Help to Defeat Tongue Cancer?
Most often it is considered that vaccines are meant to prevent infections and minor diseases. However, these days vaccines are being tested as a technique to treat people with cancer by getting linked with the immune system to identify the cancer cells and target them.
A new vaccine against HPV (Gardisil) can be helpful to treat the tongue cancer. A recent study discovered the presence of HPV in the tumor specimens of tongue and throat cancer. It is a known fact that the HPV may contribute in the origin of cervical cancer and the vaccine against HPV that is used to treat the cervical cancer can be possibly used to prevent the tongue cancer in future. Since oropharyngeal and tongue cancer involves DNA from HPV, vaccine to treat these viruses is being examined to treat these cancers. According to most of the tongue cancer research team, HPV is one of the major causes for many types of cancers.
What's New in Tongue Cancer Research?
As new researches keep on adding to the treatment options each year, various useful techniques come into existence.
A great research is being carried out to know what alterations in the DNA are responsible for converting the normal cells in the oral cavity and tongue into cancerous cells. One of the alterations often observed in DNA of tongue cancer is p53 gene mutation. Any harm to p53 DNA may lead to stimulate the growth of abnormal cells and thus development of cancer cells. Studies advocate that exams to detect these p53 gene mutations may be helpful for the detection of tongue cancer in the initial stages. These exams also allow defining the surgical margins (make certain that all the cancer cells are removed) in better way and to determine which cancer cells can respond to radiation therapy or surgery more effectively.
Growth Factors for Tumor:
Researchers have found that our body has some naturally occurring substances (hormones) that stimulate the growth of the cell. Some cells in the body tend to develop abnormally, since the growth factor gets linked with the growth receptors. In tongue cancer epidermal growth factor (EGF) is responsible for cancer development. EGF makes the cells too aggressive to get converted into cancer cells. New drugs which are particularly able to identify the cancer cells along with too many EGF receptors are being tested as new clinical trials. Preliminary studies mention that C225 (drug that recognizes the cancer cells) helps to improve the outcomes of the radiation therapy while treating squamous cell cancers of neck and head.
New Techniques of Radiation Therapy
As per a new tongue cancer research it is found that if the new radiation regimens are delivered two times each day, it could increase the cure rate of the patients. For the confirmation of these findings clinical trials are ongoing. Recent research reveals that the impact of the side effects on the salivary glands due to radiation can be reduce by using the amifostine. This drug is injected into the vein few minutes before taking the radiation treatment.
New Techniques in Chemotherapy
New researches on chemotherapy drugs are ongoing; out of these some can be injected into the arteries that feed the cancer. A combination of chemotherapy with radiotherapy can be helpful to improve the outcomes of the treatment. Another new attempt to treat the neck and head cancer is to inject the drug directly into the cancerous tumor (intralesional chemotherapy). This research is yet to be confirmed; since it is found that the injected drug gets spread into the adjoining tissues along with the other body parts quickly.
So, a number of researches are ongoing to get the best results of the cancer treatment. Tongue cancer research is carried out by considering all the available treatment options as well as the clinical trials.